MargusArizona Cardinals at San Francisco 49ers
- 4:25 PM EDT
- NFL
Match odds
No pre-game prices were stored for this game.
Box score
| ARI | Team stats | SF |
|---|---|---|
| 15 | P | 16 |
| 0 | TO | 1 |
| 16 | firstDowns | 19 |
| 260 | totalYards | 355 |
| 106 | rushingYards | 73 |
| 154 | netPassingYards | 282 |
| Player | C/ATT | YDS | TD | INT | CMP% | Y/A |
|---|---|---|---|---|---|---|
| Kyler Murray | 22-35 | 159 | 1 | 0 | 62.9% | 4.5 |
| Player | CAR | YDS | TD | Y/C |
|---|---|---|---|---|
| Trey Benson | 10 | 42 | 0 | 4.2 |
| Kyler Murray | 6 | 37 | 0 | 6.2 |
| James Conner | 9 | 22 | 0 | 2.4 |
| Greg Dortch | 1 | 5 | 0 | 5.0 |
| Emari Demercado | 2 | 0 | 0 | 0.0 |
| Player | REC | TGT | YDS | TD | Y/R |
|---|---|---|---|---|---|
| Marvin Harrison Jr. | 3 | 6 | 44 | 0 | 14.7 |
| Trey McBride | 5 | 8 | 43 | 1 | 8.6 |
| Zay Jones | 2 | 3 | 25 | 0 | 12.5 |
| James Conner | 3 | 4 | 15 | 0 | 5.0 |
| Trey Benson | 3 | 4 | 9 | 0 | 3.0 |
| Tip Reiman | 2 | 3 | 8 | 0 | 4.0 |
| Elijah Higgins | 1 | 1 | 7 | 0 | 7.0 |
| Michael Wilson | 1 | 2 | 5 | 0 | 5.0 |
| Greg Dortch | 2 | 2 | 3 | 0 | 1.5 |
| Emari Demercado | 0 | 1 | 0 | 0 | — |
| Player | TKL | SACK | INT |
|---|---|---|---|
| Mack Wilson Sr. | 12 | 0 | — |
| Akeem Davis-Gaither | 8 | 0 | — |
| Jalen Thompson | 6 | 0 | — |
| Budda Baker | 6 | 0 | — |
| Kei'Trel Clark | 5 | 0 | — |
| Dadrion Taylor-Demerson | 4 | 0 | 1 |
| Dalvin Tomlinson | 3 | 0 | — |
| Max Melton | 3 | 0 | — |
| Kitan Crawford | 2 | 0 | — |
| Zaven Collins | 2 | 0 | — |
| Cody Simon | 2 | 0 | — |
| Denzel Burke | 2 | 0 | — |
| Josh Sweat | 2 | 1 | — |
| Calais Campbell | 1 | 0 | — |
| Player | C/ATT | YDS | TD | INT | CMP% | Y/A |
|---|---|---|---|---|---|---|
| Mac Jones | 27-41 | 284 | 1 | 1 | 65.9% | 6.9 |
| Player | CAR | YDS | TD | Y/C |
|---|---|---|---|---|
| Christian McCaffrey | 17 | 52 | 0 | 3.1 |
| Brian Robinson Jr. | 2 | 22 | 0 | 11.0 |
| Mac Jones | 1 | -1 | 0 | -1.0 |
| Player | REC | TGT | YDS | TD | Y/R |
|---|---|---|---|---|---|
| Ricky Pearsall | 8 | 11 | 117 | 0 | 14.6 |
| Christian McCaffrey | 10 | 15 | 88 | 0 | 8.8 |
| Kendrick Bourne | 4 | 6 | 38 | 0 | 9.5 |
| Jake Tonges | 2 | 3 | 21 | 0 | 10.5 |
| Skyy Moore | 1 | 1 | 10 | 0 | 10.0 |
| Marquez Valdes-Scantling | 1 | 1 | 9 | 0 | 9.0 |
| Kyle Juszczyk | 1 | 1 | 1 | 1 | 1.0 |
| Player | TKL | SACK |
|---|---|---|
| Fred Warner | 11 | 0 |
| Dee Winters | 8 | 0 |
| Sam Okuayinonu | 7 | 0 |
| Marques Sigle | 7 | 0 |
| Upton Stout | 5 | 0 |
| Bryce Huff | 5 | 1 |
| Ji'Ayir Brown | 4 | 0 |
| Renardo Green | 4 | 0 |
| Jason Pinnock | 3 | 0 |
| Deommodore Lenoir | 3 | 0 |
| Jordan Elliott | 3 | 0 |
| Mykel Williams | 2 | 0 |
| C.J. West | 2 | 0 |
| Luke Gifford | 2 | 0 |
Recent form
Arizona CardinalsWLWWW
Carolina Panthers
New Orleans Saints
Las Vegas Raiders
Denver Broncos
Kansas City Chiefs
Los Angeles ChargersHead to head
2ARI wins
2SF winsLast 4 meetings with a stored final score.
League table
Full table →| # | Team | Record |
|---|---|---|
| 1 | San Francisco 49ers | 6-1 |
| 2 |  Seattle Seahawks | 4-4 |
| 3 |  Los Angeles Rams | 4-4 |
| 4 | Arizona Cardinals | 3-5 |
About this match
San Francisco 49ers beat Arizona Cardinals 16-15 on Sunday, September 21, 2025 in the NFL.
Recent form: Arizona Cardinals have won 4 of their last 5, San Francisco 49ers 4 of their last 5.
In the 4 recent meetings on record, Arizona Cardinals won 2 and San Francisco 49ers won 2. The last one finished SF 24, ARI 47 on Jan 5, 2025.
Jacoby Brissett leads Arizona Cardinals in passing yards (1,719 yds).
Brock Purdy leads San Francisco 49ers in passing yards (1,748 yds).