San Francisco 49ers odds

San Francisco 49ers next game is Las Vegas Raiders at San Francisco 49ers on 2026-11-08. Posted moneylines, spreads, and totals use the same ranking as the comparison below. Margus does not take bets.

Prices as of Sat, Nov 7, 5:55 PM EST.

Scores and roster

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Next game

Matchup	Spread	Moneyline	Total
Las Vegas RaidersSan Francisco 49ers	Spread +9.5 (+101) -9.5 (-104)	Moneyline +400 -400	Total O 51.5 (-100) U 51.5 (-102)
Scheduled · Sun, Nov 8, 4:25 PM EST · Levi's StadiumView more lines

Upcoming schedule

Matchup	Spread	Moneyline	Total
San Francisco 49ersDallas Cowboys	Spread — —	Moneyline -194 +186	Total — —
Scheduled · Sun, Nov 15, 4:25 PM EST · AT&T StadiumView more lines
Minnesota VikingsSan Francisco 49ers	Prices are not posted yet.
Scheduled · Sun, Nov 22, 8:20 PM EST · Estadio AztecaView more lines
Seattle SeahawksSan Francisco 49ers	Prices are not posted yet.
Scheduled · Sun, Nov 29, 4:25 PM EST · Levi's StadiumView more lines
San Francisco 49ersNew York Giants	Prices are not posted yet.
Scheduled · Sun, Dec 6, 1:00 PM EST · MetLife StadiumView more lines
Los Angeles RamsSan Francisco 49ers	Prices are not posted yet.
Scheduled · Sun, Dec 13, 4:25 PM EST · Levi's StadiumView more lines
San Francisco 49ersLos Angeles Chargers	Prices are not posted yet.
Scheduled · Thu, Dec 17, 8:15 PM EST · SoFi StadiumView more lines