# Jacksonville Jaguars at San Francisco 49ers odds | Sep 28, 2025 | Margus

Jacksonville Jaguars at San Francisco 49ers (NFL) is final on 2025-09-28. Final: Jacksonville Jaguars 26, San Francisco 49ers 21. Kickoff and team links are below. Stored moneylines, spreads, and totals are not posted yet. Margus does not take bets.

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## Jacksonville Jaguars at San Francisco 49ers odds

NFL. Final. Sun, Sep 28, 4:05 PM EDT. Final: Jacksonville Jaguars 26, San Francisco 49ers 21

## Moneyline, spread, and total

No eligible sportsbook prices are stored yet.